The epidemiology of food allergy in adults

Christopher Warren; Sai R. Nimmagadda; Ruchi Gupta; Michael Levin

doi:10.1016/j.anai.2022.11.026

The epidemiology of food allergy in adults

Christopher Warren^*, Sai R. Nimmagadda, Ruchi Gupta, Michael Levin

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

38 Scopus citations

Abstract

The prevalence and awareness of food allergy (FA) among US adults is arguably at a historical high, both with respect to primary immunoglobulin E–mediated food hypersensitivity and other food-triggered conditions that operate through a variety of immunologic mechanisms (eg, pollen-FA syndrome, alpha-gal syndrome, food protein-induced enterocolitis syndrome, eosinophilic esophagitis). Worryingly, not only are many adults retaining childhood-onset food allergies as they age into adulthood, it seems that many adults are experiencing adult-onset allergies to previously tolerated foods, with correspondingly adverse physical, and psychological health impacts. Consequently, this review aims to summarize what is currently known about the epidemiology and population-level burden of FA among adult populations in North America and around the globe. This article also provides insights into the natural history of these conditions and what we need to know as we look to the future to support effective care and prevent FA.

Original language	English (US)
Pages (from-to)	276-287
Number of pages	12
Journal	Annals of Allergy, Asthma and Immunology
Volume	130
Issue number	3
DOIs	https://doi.org/10.1016/j.anai.2022.11.026
State	Published - Mar 2023

Funding

Disclosures: Dr Warren reports receiving research support from the National Institutes of Health (NIH), Food Allergy Research and Education (FARE), and the Sunshine Charitable Foundation. Dr Nimmagadda reports receiving previous speaking engagements for Astra Zeneca and GlaxoSmithKline. Dr Gupta reports receiving research support from the NIH (R21 ID # AI135705, R01 ID # AI130348, U01 ID # AI138907), FARE, Melchiorre Family Foundation, Sunshine Charitable Foundation, The Walder Foundation, UnitedHealth Group, Thermo Fisher Scientific, and Genentech; and serves as a medical consultant/advisor for Genentech, Novartis, Aimmune LLC, Allergenis LLC, and FARE. Dr Gupta reports having an ownership interest in Yobee Care, Inc.

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Pulmonary and Respiratory Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.anai.2022.11.026

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title = "The epidemiology of food allergy in adults",

abstract = "The prevalence and awareness of food allergy (FA) among US adults is arguably at a historical high, both with respect to primary immunoglobulin E–mediated food hypersensitivity and other food-triggered conditions that operate through a variety of immunologic mechanisms (eg, pollen-FA syndrome, alpha-gal syndrome, food protein-induced enterocolitis syndrome, eosinophilic esophagitis). Worryingly, not only are many adults retaining childhood-onset food allergies as they age into adulthood, it seems that many adults are experiencing adult-onset allergies to previously tolerated foods, with correspondingly adverse physical, and psychological health impacts. Consequently, this review aims to summarize what is currently known about the epidemiology and population-level burden of FA among adult populations in North America and around the globe. This article also provides insights into the natural history of these conditions and what we need to know as we look to the future to support effective care and prevent FA.",

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The epidemiology of food allergy in adults

Abstract

Funding

ASJC Scopus subject areas

UN SDGs

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