TY - JOUR
T1 - The ErgoTM genome analysis and discovery system
AU - Overbeek, Ross
AU - Larsen, Niels
AU - Walunas, Theresa
AU - D’ Souza, Mark
AU - Pusch, Gordon
AU - Selkov, Eugene
AU - Liolios, Konstantinos
AU - Joukov, Viktor
AU - Kaznadzey, Denis
AU - Anderson, Iain
AU - Bhattacharyya, Anamitra
AU - Burd, Henry
AU - Gardner, Warren
AU - Hanke, Paul
AU - Kapatral, Vinayak
AU - Mikhailova, Natalia
AU - Vasieva, Olga
AU - Osterman, Andrei
AU - Vonstein, Veronika
AU - Fonstein, Michael
AU - Ivanova, Natalia
AU - Kyrpides, Nikos
PY - 2003/1/1
Y1 - 2003/1/1
N2 - The ERGO™ (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling, genetics and peer-reviewed journals to achieve a comprehensive analysis of genes and genomes. Far beyond any conventional systems that facilitate functional assignments, ERGO combines pattern-based analysis with comparative genomics by visualizing genes within the context of regulation, expression profiling, phylogenetic clusters, fusion events, networked cellular pathways and chromosomal neighborhoods of other functionally related genes. The result of this multifaceted approach is to provide an extensively curated database of the largest available integration of genomes, with a vast collection of reconstructed cellular pathways spanning all domains of life. Although access to ERGO is provided only under subscription, it is already widely used by the academic community. The current version of the system integrates 500 genomes from all domains of life in various levels of completion, 403 of which are available for subscription.
AB - The ERGO™ (http://ergo.integratedgenomics.com/ERGO/) genome analysis and discovery suite is an integration of biological data from genomics, biochemistry, high-throughput expression profiling, genetics and peer-reviewed journals to achieve a comprehensive analysis of genes and genomes. Far beyond any conventional systems that facilitate functional assignments, ERGO combines pattern-based analysis with comparative genomics by visualizing genes within the context of regulation, expression profiling, phylogenetic clusters, fusion events, networked cellular pathways and chromosomal neighborhoods of other functionally related genes. The result of this multifaceted approach is to provide an extensively curated database of the largest available integration of genomes, with a vast collection of reconstructed cellular pathways spanning all domains of life. Although access to ERGO is provided only under subscription, it is already widely used by the academic community. The current version of the system integrates 500 genomes from all domains of life in various levels of completion, 403 of which are available for subscription.
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U2 - 10.1093/nar/gkg148
DO - 10.1093/nar/gkg148
M3 - Review article
C2 - 12519973
AN - SCOPUS:0037208159
SN - 0305-1048
VL - 31
SP - 164
EP - 171
JO - Nucleic acids research
JF - Nucleic acids research
IS - 1
ER -