The Expanding and Unexpected Functions of Mitochondria Contact Sites

Laura L. Lackner

doi:10.1016/j.tcb.2019.02.009

The Expanding and Unexpected Functions of Mitochondria Contact Sites

Laura L. Lackner^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Review article › peer-review

46 Scopus citations

Abstract

Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.

Original language	English (US)
Pages (from-to)	580-590
Number of pages	11
Journal	Trends in Cell Biology
Volume	29
Issue number	7
DOIs	https://doi.org/10.1016/j.tcb.2019.02.009
State	Published - Jul 2019

Keywords

interorganelle contacts
membrane contact sites
mitochondria contact sites

ASJC Scopus subject areas

Cell Biology

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10.1016/j.tcb.2019.02.009

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title = "The Expanding and Unexpected Functions of Mitochondria Contact Sites",

abstract = "Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.",

keywords = "interorganelle contacts, membrane contact sites, mitochondria contact sites",

author = "Lackner, {Laura L.}",

note = "Funding Information: Members of the laboratory of L.L.L. are thanked for helpful discussions. I would like to apologize to colleagues whose outstanding work on mitochondria–organelle contacts could not be included owing to space limitations. This work is supported by a National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) grant ( R01GM120303 ) to L.L.L. Publisher Copyright: {\textcopyright} 2019 Elsevier Ltd",

year = "2019",

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doi = "10.1016/j.tcb.2019.02.009",

language = "English (US)",

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T1 - The Expanding and Unexpected Functions of Mitochondria Contact Sites

AU - Lackner, Laura L.

N1 - Funding Information: Members of the laboratory of L.L.L. are thanked for helpful discussions. I would like to apologize to colleagues whose outstanding work on mitochondria–organelle contacts could not be included owing to space limitations. This work is supported by a National Institutes of Health (NIH) National Institute of General Medical Sciences (NIGMS) grant ( R01GM120303 ) to L.L.L. Publisher Copyright: © 2019 Elsevier Ltd

PY - 2019/7

Y1 - 2019/7

N2 - Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.

AB - Mitochondria make functionally relevant contacts with most, if not all, other organelles in the cell. These contacts impact on mitochondrial behavior and function as well as on a wide variety of cellular functions. Many recent advances have been made in the rapidly growing field of mitochondria contact site biology, and these advances have expanded the known functions of mitochondria contact sites in exciting and unexpected ways.

KW - interorganelle contacts

KW - membrane contact sites

KW - mitochondria contact sites

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DO - 10.1016/j.tcb.2019.02.009

M3 - Review article

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VL - 29

SP - 580

EP - 590

JO - Trends in Cell Biology

JF - Trends in Cell Biology

SN - 0962-8924

IS - 7

ER -

The Expanding and Unexpected Functions of Mitochondria Contact Sites

Abstract

Keywords

ASJC Scopus subject areas

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