The experience of pain and redness in patients with moderate to severe plaque psoriasis

Mona L. Martin; Kenneth Gordon; Lionel Pinto; Donald M. Bushnell; Dina Chau; Hema N. Viswanathan

doi:10.3109/09546634.2014.996514

The experience of pain and redness in patients with moderate to severe plaque psoriasis

Mona L. Martin^*, Kenneth Gordon, Lionel Pinto, Donald M. Bushnell, Dina Chau, Hema N. Viswanathan

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

Introduction: The Psoriasis Symptom Inventory is a patient-reported outcome instrument that assesses severity of psoriasis signs and symptoms. In early qualitative research, patients reported pain related to psoriasis skin lesions and redness of affected areas of skin as key symptoms. Methods: Individual concept elicitation interviews and cognitive interviews were conducted in adults with moderate to severe plaque psoriasis. Interviews were audio-recorded and transcribed. Concepts were identified, coded and grouped by similar content using Atlas.ti software. Results were evaluated using qualitative research methods. Results: Of 30 patients recruited, 20 patients participated in concept elicitation interviews and 10 participated in cognitive interviews. Concept codes for skin pain and descriptions of color comprised 11% and 15%, respectively, of all symptom-related expressions. Of 90 pain-related expressions, 22 were about pain related to unconscious scratching and 68 were about pain from the psoriasis lesions. Of 199 color-related expressions, 72 were about red or reddish lesion color. Patients with darker skin tones were found to interpret redness consistently. Discussion: These results provide further support to content validity of pain and redness concepts in the Psoriasis Symptom Inventory. Conclusions: Symptoms of skin pain and redness are highly relevant to patients with psoriasis.

Original language	English (US)
Pages (from-to)	401-405
Number of pages	5
Journal	Journal of Dermatological Treatment
Volume	26
Issue number	5
DOIs	https://doi.org/10.3109/09546634.2014.996514
State	Published - Sep 3 2015

Funding

M. M. and D. M. B. are employees of Health Research Associates, who received funding for this study from Amgen Inc. K. G. has been an investigator and received research support from: AbbVie Inc., Amgen Inc., Eli Lilly and Co., Celgene Corp., Merck & Co. and Novartis AG and has been a consultant for AbbVie Inc., Amgen Inc., Eli Lilly and Co., Celgene Corp., Novartis AG and Pfizer Inc. D. C., L. P. and H. N. V. are employees and shareholders of Amgen Inc. Jon Nilsen (Amgen Inc.) and Julia R. Gage (on behalf of Amgen Inc.) provided assistance with writing the manuscript. This study was funded by Amgen Inc.

Keywords

Psoriasis Symptom Inventory
Psoriasis signs and symptoms
severity

ASJC Scopus subject areas

Dermatology

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10.3109/09546634.2014.996514

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title = "The experience of pain and redness in patients with moderate to severe plaque psoriasis",

abstract = "Introduction: The Psoriasis Symptom Inventory is a patient-reported outcome instrument that assesses severity of psoriasis signs and symptoms. In early qualitative research, patients reported pain related to psoriasis skin lesions and redness of affected areas of skin as key symptoms. Methods: Individual concept elicitation interviews and cognitive interviews were conducted in adults with moderate to severe plaque psoriasis. Interviews were audio-recorded and transcribed. Concepts were identified, coded and grouped by similar content using Atlas.ti software. Results were evaluated using qualitative research methods. Results: Of 30 patients recruited, 20 patients participated in concept elicitation interviews and 10 participated in cognitive interviews. Concept codes for skin pain and descriptions of color comprised 11% and 15%, respectively, of all symptom-related expressions. Of 90 pain-related expressions, 22 were about pain related to unconscious scratching and 68 were about pain from the psoriasis lesions. Of 199 color-related expressions, 72 were about red or reddish lesion color. Patients with darker skin tones were found to interpret redness consistently. Discussion: These results provide further support to content validity of pain and redness concepts in the Psoriasis Symptom Inventory. Conclusions: Symptoms of skin pain and redness are highly relevant to patients with psoriasis.",

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author = "Martin, {Mona L.} and Kenneth Gordon and Lionel Pinto and Bushnell, {Donald M.} and Dina Chau and Viswanathan, {Hema N.}",

note = "Funding Information: M. M. and D. M. B. are employees of Health Research Associates, who received funding for this study from Amgen Inc. K. G. has been an investigator and received research support from: AbbVie Inc., Amgen Inc., Eli Lilly and Co., Celgene Corp., Merck & Co. and Novartis AG and has been a consultant for AbbVie Inc., Amgen Inc., Eli Lilly and Co., Celgene Corp., Novartis AG and Pfizer Inc. D. C., L. P. and H. N. V. are employees and shareholders of Amgen Inc. Jon Nilsen (Amgen Inc.) and Julia R. Gage (on behalf of Amgen Inc.) provided assistance with writing the manuscript. This study was funded by Amgen Inc. Publisher Copyright: {\textcopyright} 2015 Informa UK Ltd.",

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AU - Chau, Dina

AU - Viswanathan, Hema N.

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N2 - Introduction: The Psoriasis Symptom Inventory is a patient-reported outcome instrument that assesses severity of psoriasis signs and symptoms. In early qualitative research, patients reported pain related to psoriasis skin lesions and redness of affected areas of skin as key symptoms. Methods: Individual concept elicitation interviews and cognitive interviews were conducted in adults with moderate to severe plaque psoriasis. Interviews were audio-recorded and transcribed. Concepts were identified, coded and grouped by similar content using Atlas.ti software. Results were evaluated using qualitative research methods. Results: Of 30 patients recruited, 20 patients participated in concept elicitation interviews and 10 participated in cognitive interviews. Concept codes for skin pain and descriptions of color comprised 11% and 15%, respectively, of all symptom-related expressions. Of 90 pain-related expressions, 22 were about pain related to unconscious scratching and 68 were about pain from the psoriasis lesions. Of 199 color-related expressions, 72 were about red or reddish lesion color. Patients with darker skin tones were found to interpret redness consistently. Discussion: These results provide further support to content validity of pain and redness concepts in the Psoriasis Symptom Inventory. Conclusions: Symptoms of skin pain and redness are highly relevant to patients with psoriasis.

AB - Introduction: The Psoriasis Symptom Inventory is a patient-reported outcome instrument that assesses severity of psoriasis signs and symptoms. In early qualitative research, patients reported pain related to psoriasis skin lesions and redness of affected areas of skin as key symptoms. Methods: Individual concept elicitation interviews and cognitive interviews were conducted in adults with moderate to severe plaque psoriasis. Interviews were audio-recorded and transcribed. Concepts were identified, coded and grouped by similar content using Atlas.ti software. Results were evaluated using qualitative research methods. Results: Of 30 patients recruited, 20 patients participated in concept elicitation interviews and 10 participated in cognitive interviews. Concept codes for skin pain and descriptions of color comprised 11% and 15%, respectively, of all symptom-related expressions. Of 90 pain-related expressions, 22 were about pain related to unconscious scratching and 68 were about pain from the psoriasis lesions. Of 199 color-related expressions, 72 were about red or reddish lesion color. Patients with darker skin tones were found to interpret redness consistently. Discussion: These results provide further support to content validity of pain and redness concepts in the Psoriasis Symptom Inventory. Conclusions: Symptoms of skin pain and redness are highly relevant to patients with psoriasis.

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The experience of pain and redness in patients with moderate to severe plaque psoriasis

Abstract

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Keywords

ASJC Scopus subject areas

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