TY - JOUR
T1 - The external glial limiting membrane in Macaca
T2 - Ultrastructure of a laminated glioepithelium
AU - Bondareff, William
AU - McLone, David G.
PY - 1973/3
Y1 - 1973/3
N2 - The external glial limiting membrane in Macaca is a multilaminar epithelium‐like mantle formed by the perikarya and interdigitating cell processes of astrocytes. It is separated from the overlying subarachnoid space by a typical basement membrane. Tonofilaments, about 100 Å in diameter, course through the cytoplasm of the processes in sheaths which run in different planes in successive layers of the mantle, forming a course brushwork. Beneath the surface plasma membrane of the superficial astrocytes is a filamentous layer, 500–700 Å thick, which is composed of microfilaments, about 50 Å in diameter. These microfilaments were continuous with the inner aspect of the plasma membrane. The tonofilaments appeared to terminate in the microfilamentous network. The similarity of these microfilaments to the cytocholasin B‐sensitive microfilaments of epithelial cells suggested contractile properties and their participation in the motility of glial cells at the border of the brain and subarachnoid space.
AB - The external glial limiting membrane in Macaca is a multilaminar epithelium‐like mantle formed by the perikarya and interdigitating cell processes of astrocytes. It is separated from the overlying subarachnoid space by a typical basement membrane. Tonofilaments, about 100 Å in diameter, course through the cytoplasm of the processes in sheaths which run in different planes in successive layers of the mantle, forming a course brushwork. Beneath the surface plasma membrane of the superficial astrocytes is a filamentous layer, 500–700 Å thick, which is composed of microfilaments, about 50 Å in diameter. These microfilaments were continuous with the inner aspect of the plasma membrane. The tonofilaments appeared to terminate in the microfilamentous network. The similarity of these microfilaments to the cytocholasin B‐sensitive microfilaments of epithelial cells suggested contractile properties and their participation in the motility of glial cells at the border of the brain and subarachnoid space.
UR - http://www.scopus.com/inward/record.url?scp=0015590991&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0015590991&partnerID=8YFLogxK
U2 - 10.1002/aja.1001360303
DO - 10.1002/aja.1001360303
M3 - Article
C2 - 4634161
AN - SCOPUS:0015590991
SN - 0002-9106
VL - 136
SP - 277
EP - 295
JO - American Journal of Anatomy
JF - American Journal of Anatomy
IS - 3
ER -