The flow of aqueous humor through micro-porous filters

M. Johnson, C. R. Ethier, R. D. Kamm, W. M. Grant, D. L. Epstein, D. Gaasterland

Research output: Contribution to journalArticlepeer-review

23 Scopus citations

Abstract

Flow resistance was measured as bovine and primate aqueous humor was passed through Nuclepore polycarbonate filters having flow dimensions similar to those found within the juxtacanalicular meshwork of the aqueous outflow network. The results indicate that aqueous humor has a greater flow resistance than isotonic saline; this greater resistance is attributable to proteins or glycoproteins in aqueous humor that obstruct the filters. If the same phenomenon is operative in the aqueous outflow network, it would help to explain discrepancies between calculated and measured aqueous outflow resistance.

Original languageEnglish (US)
Pages (from-to)92-97
Number of pages6
JournalInvestigative Ophthalmology and Visual Science
Volume27
Issue number1
StatePublished - 1986

ASJC Scopus subject areas

  • Ophthalmology
  • Sensory Systems
  • Cellular and Molecular Neuroscience

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