Abstract
Probes for restriction fragment length polymorphisms mapping between Xp21 and Xq22.3 have been used in a linkage study of incontinentia pigmenti (IP). Six independent sporadic cases of disorders resembling IP with X‐autosome translocations involving the same X chromosome breakpoint (Xp11) have been reported. These observations suggest that the IP gene may be located in the Xp11 chromosomal region. However, the linkage study with DNA probes has failed to confirm this localisation.
Original language | English (US) |
---|---|
Pages (from-to) | 1-6 |
Number of pages | 6 |
Journal | Clinical Genetics |
Volume | 34 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1988 |
Keywords
- DNA probes
- incontinentia pigmenti
- linkage
ASJC Scopus subject areas
- Genetics
- Genetics(clinical)