The Generalized Atrophic Benign Form of Junctional Epidermolysis Bullosa: Experience with Four Patients in the United States

Amy S. Paller*, Jo David Fine, Sidney Kaplan, Roger W. Pearson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

We encountered four patients in the United States with the generalized atrophic benign form of junctional epidermolysis bullosa (epidermolysis bullosa atrophicans generalisata mitis, nonlethal junctional epidermolysis bullosa). Prior to the performance of definitive diagnostic studies, each patient had been thought for at least a decade to have either a dystrophic or simplex form of epidermolysis bullosa. Each patient had generalized blisters since birth that healed with atrophy and mild scarring but without milia or contractures. Two of the four patients had experienced laryngeal involvement during childhood. In each patient, correct diagnosis was finally established by either electron microscopic examination or immunofluorescence mapping of skin sections from induced blisters.

Original languageEnglish (US)
Pages (from-to)704-710
Number of pages7
JournalArchives of dermatology
Volume122
Issue number6
DOIs
StatePublished - Jun 1986

ASJC Scopus subject areas

  • Dermatology

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