The global epidemiology of SLE: narrowing the knowledge gaps

Megan R.W. Barber*, Titilola Falasinnu, Rosalind Ramsey-Goldman, Ann E. Clarke

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

SLE is a global health concern that unevenly affects certain ethnic/racial groups. Individuals of Asian, Black, Hispanic and Indigenous ethnicity/race are amongst those who experience increased prevalence, incidence, morbidity and mortality. Population-based surveillance studies from many regions are few and often still in nascent stages. Many of these areas are challenged by restricted access to diagnostics and therapeutics. Without accurately capturing the worldwide burden and distribution of SLE, appropriately dedicating resources to improve global SLE outcomes may be challenging. This review discusses recent SLE epidemiological studies, highlighting the challenges and emerging opportunities in low- and middle-income countries. We suggest means of closing these gaps to better address the global health need in SLE.

Original languageEnglish (US)
Pages (from-to)I4-I9
JournalRheumatology (United Kingdom)
Volume62
DOIs
StatePublished - Apr 1 2023

Funding

T.F. (K01AR079039) received funding from the NIH National Institute of Arthritis and Musculoskeletal and Skin Diseases. R.R.-G. is supported as the Gallagher Research Professor of Rheumatology at Northwestern University Feinberg School of Medicine and by the following NIH grants (P30 AR072579, R01 AR071091, R01AR073850, R01 AR080089, R21 AI171491 and R01 AI170938), and Department of Defence (W81XWH2010692). A.E.C. holds The Arthritis Society Chair in Rheumatic Diseases at the University of Calgary.

Keywords

  • SLE
  • epidemiology
  • health disparities
  • incidence
  • low- and middle-income countries
  • lupus
  • prevalence

ASJC Scopus subject areas

  • Rheumatology
  • Pharmacology (medical)

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