TY - JOUR
T1 - The human cytolytic T lymphocyte response to transplantation antigens
AU - Krensky, Alan M.
PY - 1985/12
Y1 - 1985/12
N2 - Cytolytic T lymphocytes are important effectors in the immune response to allografts, viral infections, and some tumors. Cytolytic T lymphocyte lines and clones have been generated and used to define functionally relevant effector and target cell surface molecules. The major target antigens of the human allogeneic response are the major histocompatibility complex antigens. Functionally relevant effector antigens include LFA-1, LFA-2, LFA-3, OKT4, OKT8, OKT3, and Ti, the T cell receptor. The diagnostic and therapeutic implications of T cell surface molecules are discussed.
AB - Cytolytic T lymphocytes are important effectors in the immune response to allografts, viral infections, and some tumors. Cytolytic T lymphocyte lines and clones have been generated and used to define functionally relevant effector and target cell surface molecules. The major target antigens of the human allogeneic response are the major histocompatibility complex antigens. Functionally relevant effector antigens include LFA-1, LFA-2, LFA-3, OKT4, OKT8, OKT3, and Ti, the T cell receptor. The diagnostic and therapeutic implications of T cell surface molecules are discussed.
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U2 - 10.1203/00006450-198512000-00001
DO - 10.1203/00006450-198512000-00001
M3 - Article
C2 - 3878492
AN - SCOPUS:0022394736
SN - 0031-3998
VL - 19
SP - 1231
EP - 1234
JO - Pediatric research
JF - Pediatric research
IS - 12
ER -