The human mycobiome

Patrick C. Seed*

*Corresponding author for this work

Research output: Contribution to journalArticle

38 Scopus citations

Abstract

Fungi are fundamental to the human microbiome, the collection of microbes distributed across and within the body, and the microbiome has been shown, in total, to modify fundamental human physiology, including energy acquisition, vitamin-cofactor availability, xenobiotic metabolism, immune development and function, and even neurological development and behavior. Here, a comprehensive review of current knowledge about the mycobiome, the collective of fungi within the microbiome, highlights methods for its study, diversity between body sites, and dynamics during human development, health, and disease. Earlystage studies show interactions between the mycobiome and other microbes, with host physiology, and in pathogenic and mutualistic phenotypes. Current research portends a vital role for the mycobiome in human health and disease.

Original languageEnglish (US)
Article numbera019810
JournalCold Spring Harbor Perspectives in Medicine
Volume5
Issue number5
DOIs
StatePublished - May 1 2015

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ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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