The hunt for the biological transistor

Julius Lucks; Adam Arkin

doi:10.1109/MSPEC.2011.5719724

The hunt for the biological transistor

Julius Lucks^*, Adam Arkin

^*Corresponding author for this work

Chemical and Biological Engineering

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

In 1977, a small group of researchers in California changed the world when they wrangled a common gut bacterium into producing a human protein. Using every technique in the book - and inventing some of their own - they scavenged, snipped, and glued together genetic components to synthesize a tiny filament of DNA. They then inserted the new segment into some Escherichia coli cells, tricking them into making the human hormone somatostatin.

Original language	English (US)
Article number	5719724
Pages (from-to)	38-43
Number of pages	6
Journal	IEEE Spectrum
Volume	48
Issue number	3
DOIs	https://doi.org/10.1109/MSPEC.2011.5719724
State	Published - Mar 1 2011

Keywords

Biological information theory
DNA
Genetics
Logic gates
Proteins
Research and development
RNA

ASJC Scopus subject areas

Electrical and Electronic Engineering

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10.1109/MSPEC.2011.5719724

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The hunt for the biological transistor

Abstract

Keywords

ASJC Scopus subject areas

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