The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self‐association of IgG‐rheumatoid factors

Richard M. Pope; Mart Mannik; Bruce C. Gilliland; David C. Teller

doi:10.1002/art.1780180201

The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self‐association of IgG‐rheumatoid factors

Richard M. Pope, Mart Mannik^*, Bruce C. Gilliland, David C. Teller

^*Corresponding author for this work

Medicine, Rheumatology Division

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

Three patients with rheumatoid arthritis and abundant circulating intermediate complexes were studied. Two of these patients presented with the hyperviscosity syndrome. All 3 patients had markedly elevated plasma and blood viscosity, and the intermediate complexes were thought to be responsible for the increased viscosity. Studies on the isolated intermediate complexes revealed that they were formed by self‐association of IgG‐rheumatoid factors.

Original language	English (US)
Pages (from-to)	97-106
Number of pages	10
Journal	Arthritis & Rheumatism
Volume	18
Issue number	2
DOIs	https://doi.org/10.1002/art.1780180201
State	Published - 1975

ASJC Scopus subject areas

Pharmacology (medical)
Immunology and Allergy
Rheumatology
Immunology

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abstract = "Three patients with rheumatoid arthritis and abundant circulating intermediate complexes were studied. Two of these patients presented with the hyperviscosity syndrome. All 3 patients had markedly elevated plasma and blood viscosity, and the intermediate complexes were thought to be responsible for the increased viscosity. Studies on the isolated intermediate complexes revealed that they were formed by self‐association of IgG‐rheumatoid factors.",

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The hyperviscosity syndrome in rheumatoid arthritis due to intermediate complexes formed by self‐association of IgG‐rheumatoid factors

Abstract

ASJC Scopus subject areas

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