The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases

Stephen D Miller; William J. Karpus

doi:10.1016/0167-5699(94)90173-2

The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases

Stephen D Miller^*, William J. Karpus

^*Corresponding author for this work

Microbiology-Immunology

Research output: Contribution to journal › Article › peer-review

167 Scopus citations

Abstract

A variety of experimental approaches are currently being evaluated for controlling CD4⁺ T helper 1 (Th1)-mediated autoimmune pathology. Here, Stephen Miller and William Karpus compare and contrast the efficacies of various antigen-specific regulatory strategies. Particular emphasis is placed on the mechanisms of peripheral immune tolerance and how this may be used in the treatment and analysis of the pathologic T-cell repertoire in autoimmune and virus-induced demyelinating diseases.

Original language	English (US)
Pages (from-to)	356-361
Number of pages	6
Journal	Trends in Immunology
Volume	15
Issue number	8
DOIs	https://doi.org/10.1016/0167-5699(94)90173-2
State	Published - Jan 1 1994

ASJC Scopus subject areas

Immunology

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10.1016/0167-5699(94)90173-2

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abstract = "A variety of experimental approaches are currently being evaluated for controlling CD4+ T helper 1 (Th1)-mediated autoimmune pathology. Here, Stephen Miller and William Karpus compare and contrast the efficacies of various antigen-specific regulatory strategies. Particular emphasis is placed on the mechanisms of peripheral immune tolerance and how this may be used in the treatment and analysis of the pathologic T-cell repertoire in autoimmune and virus-induced demyelinating diseases.",

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The immunopathogenesis and regulation of T-cell-mediated demyelinating diseases

Abstract

ASJC Scopus subject areas

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