Most studies suggest that the pathogenesis of Multiple Sclerosis (MS) is based on immune mechanisms of myelin injury. In addition, a viral infection, possibly established in the first few years of the patient's life, may be crucial in setting the stage for such immune mediated injury when acting on the appropriate genetic background. Of the several models of virus-induced demyelination described in the last two decades, Theiler's murine encephalomyelitis virus (TMEV) infection has emerged as one of the best models for MS.
|Original language||English (US)|
|Number of pages||6|
|Journal||Italian Journal of Neurological Sciences|
|Issue number||9 Suppl 14|
|State||Published - Dec 1992|
ASJC Scopus subject areas
- Clinical Neurology