The impact of documentation of severe acute kidney injury on mortality

Francis Perry Wilson*, Amar D. Bansal, Sravan K. Jasti, Jennie J. Lin, Michael G S Shashaty, Jeffrey S. Berns, Harold I. Feldman, Barry D. Fuchs

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

37 Scopus citations


Aims: Modification of the mortality risk associated with acute kidney injury (AKI) necessitates recognition of AKI when it occurs. We sought to determine whether formal documentation of AKI in the medical record, assessed by billing codes for AKI, would be associated with improved clinical outcomes. Methods: Retrospective cohort study conducted at three hospitals within a single university health system. Adults without severe underlying kidney disease who suffered in-hospital AKI as defined by a doubling of baseline creatinine (n = 5,438) were included. Those whose AKI was formally documented according to discharge billing codes were compared to those without such documentation in terms of 30-day mortality. Results: Formal documentation of AKI occurred in 2,325 patients (43%). Higher baseline creatinine, higher peak creatinine, medical admission status, and higher Sequential Organ Failure Assessment (SOFA) score were strongly associated with documentation of AKI. After adjustment for severity of disease, formal AKI documentation was associated with reduced 30-day mortality - OR 0.81 (0.68 - 0.96, p = 0.02). Patients with formal documentation were more likely to receive a nephrology consultation (31% vs. 6%, p < 0.001) and fluid boluses (64% vs. 45%, p < 0.001), and had a more rapid discontinuation of angiotensin- converting enzyme inhibitor and angiotensin-receptor blocker medications (HR 2.04, CI 1.69 - 2.46, p < 0.001). Conclusions: Formal documentation of AKI is associated with improved survival after adjustment for illness severity among patients with creatinine-defined AKI.

Original languageEnglish (US)
Pages (from-to)417-425
Number of pages9
JournalClinical Nephrology
Issue number6
StatePublished - Dec 2013


  • Acute kidney injury
  • Cohort studies
  • Documentation
  • International classification of diseases
  • mortality

ASJC Scopus subject areas

  • Nephrology


Dive into the research topics of 'The impact of documentation of severe acute kidney injury on mortality'. Together they form a unique fingerprint.

Cite this