The impact of race on metabolic, graft, and patient outcomes after pancreas transplantation

Haley M. Gonzales*, David J. Taber, Satish Nadig, Neha Patel, Angello Lin, Prabhakar K. Baliga, Vinayak S. Rohan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


Background: Racial disparities following pancreas transplantation (PTX) are poorly defined. Methods: This was a large-scale, single-center, longitudinal cohort study including adult PTX recipients. Patients were grouped by race to allow for comparisons. Results: 287 PTX recipients were included; 125 (43.5%) were African American (AA). At baseline, AAs had a significantly higher proportion of T2DM (19.4% vs. 5.7%, p = 0.001), were younger, and more likely to be female. AAs experienced significantly higher rates of pancreatic leaks and post-operative bleeding. PTX rejection was comparable, however, kidney rejection tended to be higher among AA SPKs. Long-term mean HgbA1C levels were significantly higher among AAs (6.9% vs. 6.3%, p = 0.039). Patient and graft survival was comparable between groups, but early patient survival tended to be lower in AAs. Conclusions: This study demonstrated significant perioperative health disparities among AA PTX recipients, including poorer glycemic control and more early deaths, despite similar long-term patient and graft survival.

Original languageEnglish (US)
Pages (from-to)812-816
Number of pages5
JournalAmerican journal of surgery
Issue number4
StatePublished - Apr 2022
Externally publishedYes


  • African americans
  • Diabetes mellitus
  • Graft survival
  • Healthcare disparities
  • Pancreas transplantation

ASJC Scopus subject areas

  • Surgery


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