The Impact of Social Distancing for COVID-19 upon Diagnosis of Kawasaki Disease

Stanford Shulman; Bessey Geevarghese; Kwang Youn Kim; Anne Rowley

doi:10.1093/jpids/piab013

The Impact of Social Distancing for COVID-19 upon Diagnosis of Kawasaki Disease

Stanford Shulman^*, Bessey Geevarghese, Kwang Youn Kim, Anne Rowley

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mitigation policies have been associated with profound decreases in diagnoses of common childhood respiratory infections. A leading theory of etiology of Kawasaki disease (KD) is that it is triggered by presently unidentified ubiquitous respiratory agent. We document that mitigation policies instituted in mid-March 2020 were associated with strikingly fewer diagnoses of KD in April-December 2020 compared with the same period in the previous 8 years (P =. 01), a >67% decline. This finding supports the hypothesis that KD is caused by a respiratory-transmitted agent.

Original language	English (US)
Pages (from-to)	742-744
Number of pages	3
Journal	Journal of the Pediatric Infectious Diseases Society
Volume	10
Issue number	6
DOIs	https://doi.org/10.1093/jpids/piab013
State	Published - Jun 1 2021

Funding

This work was supported by NIH AI150719 to AR and the Kawasaki Disease Fund of the Ann & Robert H. Lurie Children’s Hospital of Chicago.

Keywords

COVID-19
Kawasaki disease
mitigation
respiratory transmission
social distancing

ASJC Scopus subject areas

General Medicine

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10.1093/jpids/piab013

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title = "The Impact of Social Distancing for COVID-19 upon Diagnosis of Kawasaki Disease",

abstract = "Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mitigation policies have been associated with profound decreases in diagnoses of common childhood respiratory infections. A leading theory of etiology of Kawasaki disease (KD) is that it is triggered by presently unidentified ubiquitous respiratory agent. We document that mitigation policies instituted in mid-March 2020 were associated with strikingly fewer diagnoses of KD in April-December 2020 compared with the same period in the previous 8 years (P =. 01), a >67% decline. This finding supports the hypothesis that KD is caused by a respiratory-transmitted agent.",

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AB - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mitigation policies have been associated with profound decreases in diagnoses of common childhood respiratory infections. A leading theory of etiology of Kawasaki disease (KD) is that it is triggered by presently unidentified ubiquitous respiratory agent. We document that mitigation policies instituted in mid-March 2020 were associated with strikingly fewer diagnoses of KD in April-December 2020 compared with the same period in the previous 8 years (P =. 01), a >67% decline. This finding supports the hypothesis that KD is caused by a respiratory-transmitted agent.

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The Impact of Social Distancing for COVID-19 upon Diagnosis of Kawasaki Disease

Abstract

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