The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices

Saima Aslam; Jennifer Cowger; Palak Shah; Valentina Stosor; Hannah Copeland; Anna Reed; David Morales; Gerard Giblin; Jacob Mathew; Orla Morrissey; Paola Morejon; Alina Nicoara; Ezequiel Molina

doi:10.1016/j.healun.2024.03.004

The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices

Saima Aslam^*, Jennifer Cowger, Palak Shah, Valentina Stosor, Hannah Copeland, Anna Reed, David Morales, Gerard Giblin, Jacob Mathew, Orla Morrissey, Paola Morejon, Alina Nicoara, Ezequiel Molina

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Infections remain a significant concern in patients receiving mechanical circulatory support (MCS), encompassing both durable and acute devices. This consensus manuscript provides updated definitions for infections associated with durable MCS devices and new definitions for infections in acute MCS, integrating a comprehensive review of existing literature and collaborative discussions among multidisciplinary specialists. By establishing consensus definitions, we seek to enhance clinical care, facilitate consistent reporting in research studies, and ultimately improve outcomes for patients receiving MCS.

Original language	English (US)
Pages (from-to)	1039-1050
Number of pages	12
Journal	Journal of Heart and Lung Transplantation
Volume	43
Issue number	7
DOIs	https://doi.org/10.1016/j.healun.2024.03.004
State	Published - Jul 2024

Funding

Stosor: NIH (grant support to institution), CDC (grant support to institution), Eli Lilly & Company (grant support to institution), DiaSorin S.p.A. (consultant) Aslam: Cystic Fibrosis Foundation 2023 Leadership and Design Grant # 006366123 - AslamBCC Phage Clinical Trial Planning Grant (grant support to institution), Armata Pharmaceuticals (grant support to institution), Contrafect Corporation (grant support to institution), NIH/NIAID U19-U1AI157981 (grant support to institution), NIH/ NIAID 5U01AI138897-S04 (grant support to institution), NIH/NIAID 1 UO1-AI134591-01 (grant support to institution), BioMx (consultant), Phico (consultant), Rocket Pharmaceuticals, Pherecydes Pharma (medical advisory board), Phiogen (medical advisory board)

Keywords

ECMO
LVAD
MCS
definitions
infection

ASJC Scopus subject areas

Surgery
Pulmonary and Respiratory Medicine
Cardiology and Cardiovascular Medicine
Transplantation

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.healun.2024.03.004

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Aslam, S., Cowger, J., Shah, P., Stosor, V., Copeland, H., Reed, A., Morales, D., Giblin, G., Mathew, J., Morrissey, O., Morejon, P., Nicoara, A., & Molina, E. (2024). The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices. Journal of Heart and Lung Transplantation, 43(7), 1039-1050. https://doi.org/10.1016/j.healun.2024.03.004

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title = "The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices",

abstract = "Infections remain a significant concern in patients receiving mechanical circulatory support (MCS), encompassing both durable and acute devices. This consensus manuscript provides updated definitions for infections associated with durable MCS devices and new definitions for infections in acute MCS, integrating a comprehensive review of existing literature and collaborative discussions among multidisciplinary specialists. By establishing consensus definitions, we seek to enhance clinical care, facilitate consistent reporting in research studies, and ultimately improve outcomes for patients receiving MCS.",

keywords = "ECMO, LVAD, MCS, definitions, infection",

author = "Saima Aslam and Jennifer Cowger and Palak Shah and Valentina Stosor and Hannah Copeland and Anna Reed and David Morales and Gerard Giblin and Jacob Mathew and Orla Morrissey and Paola Morejon and Alina Nicoara and Ezequiel Molina",

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language = "English (US)",

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Aslam, S, Cowger, J, Shah, P, Stosor, V, Copeland, H, Reed, A, Morales, D, Giblin, G, Mathew, J, Morrissey, O, Morejon, P, Nicoara, A & Molina, E 2024, 'The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices', Journal of Heart and Lung Transplantation, vol. 43, no. 7, pp. 1039-1050. https://doi.org/10.1016/j.healun.2024.03.004

TY - JOUR

T1 - The International Society for Heart and Lung Transplantation (ISHLT)

T2 - 2024 infection definitions for durable and acute mechanical circulatory support devices

AU - Aslam, Saima

AU - Cowger, Jennifer

AU - Shah, Palak

AU - Stosor, Valentina

AU - Copeland, Hannah

AU - Reed, Anna

AU - Morales, David

AU - Giblin, Gerard

AU - Mathew, Jacob

AU - Morrissey, Orla

AU - Morejon, Paola

AU - Nicoara, Alina

AU - Molina, Ezequiel

PY - 2024/7

Y1 - 2024/7

N2 - Infections remain a significant concern in patients receiving mechanical circulatory support (MCS), encompassing both durable and acute devices. This consensus manuscript provides updated definitions for infections associated with durable MCS devices and new definitions for infections in acute MCS, integrating a comprehensive review of existing literature and collaborative discussions among multidisciplinary specialists. By establishing consensus definitions, we seek to enhance clinical care, facilitate consistent reporting in research studies, and ultimately improve outcomes for patients receiving MCS.

AB - Infections remain a significant concern in patients receiving mechanical circulatory support (MCS), encompassing both durable and acute devices. This consensus manuscript provides updated definitions for infections associated with durable MCS devices and new definitions for infections in acute MCS, integrating a comprehensive review of existing literature and collaborative discussions among multidisciplinary specialists. By establishing consensus definitions, we seek to enhance clinical care, facilitate consistent reporting in research studies, and ultimately improve outcomes for patients receiving MCS.

KW - ECMO

KW - LVAD

KW - MCS

KW - definitions

KW - infection

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AN - SCOPUS:85193432948

SN - 1053-2498

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JO - Journal of Heart and Lung Transplantation

JF - Journal of Heart and Lung Transplantation

IS - 7

ER -

The International Society for Heart and Lung Transplantation (ISHLT): 2024 infection definitions for durable and acute mechanical circulatory support devices

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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