The kinetics of charge recombination in DNA hairpins controlled by counterions

Gail S. Blaustein, Frederick D Lewis, Alexander L. Burin, Rajesh Shrestha

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

The charge recombination rate in DNA hairpins is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd ∈+∈) and stilbene acceptor (Sa-) linkers separated by an AT bridge has a double exponential form. We suggest that this dependence is associated with two tunneling channels distinguished by the presence or absence of the Cl- counterion bound to Sd ∈+∈. Experiment-based estimates of counterion binding parameters agree within reasonable expectations. A control experiment replacing the Cl- ion with other halide ions is suggested. Counterion substitution allows modification of the charge recombination rate in either direction by orders of magnitude.

Original languageEnglish (US)
Title of host publicationComputational Science - ICCS 2009 - 9th International Conference, Proceedings
Pages189-196
Number of pages8
EditionPART 2
DOIs
Publication statusPublished - Sep 17 2009
Event9th International Conference on Computational Science, ICCS 2009 - Baton Rouge, LA, United States
Duration: May 25 2009May 27 2009

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
NumberPART 2
Volume5545 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Other

Other9th International Conference on Computational Science, ICCS 2009
CountryUnited States
CityBaton Rouge, LA
Period5/25/095/27/09

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Keywords

  • Charge transfer
  • Counterions
  • DNA hairpin

ASJC Scopus subject areas

  • Theoretical Computer Science
  • Computer Science(all)

Cite this

Blaustein, G. S., Lewis, F. D., Burin, A. L., & Shrestha, R. (2009). The kinetics of charge recombination in DNA hairpins controlled by counterions. In Computational Science - ICCS 2009 - 9th International Conference, Proceedings (PART 2 ed., pp. 189-196). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 5545 LNCS, No. PART 2). https://doi.org/10.1007/978-3-642-01973-9_21