The kinetics of charge recombination in DNA hairpins controlled by counterions

Gail S. Blaustein; Frederick D. Lewis; Alexander L. Burin; Rajesh Shrestha

doi:10.1007/978-3-642-01973-9_21

The kinetics of charge recombination in DNA hairpins controlled by counterions

Gail S. Blaustein, Frederick D. Lewis, Alexander L. Burin, Rajesh Shrestha

Chemistry

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

2 Scopus citations

Abstract

The charge recombination rate in DNA hairpins is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd ^∈+∈) and stilbene acceptor (Sa^-) linkers separated by an AT bridge has a double exponential form. We suggest that this dependence is associated with two tunneling channels distinguished by the presence or absence of the Cl^- counterion bound to Sd ^∈+∈. Experiment-based estimates of counterion binding parameters agree within reasonable expectations. A control experiment replacing the Cl^- ion with other halide ions is suggested. Counterion substitution allows modification of the charge recombination rate in either direction by orders of magnitude.

Original language	English (US)
Title of host publication	Computational Science - ICCS 2009 - 9th International Conference, Proceedings
Pages	189-196
Number of pages	8
Edition	PART 2
DOIs	https://doi.org/10.1007/978-3-642-01973-9_21
State	Published - 2009
Event	9th International Conference on Computational Science, ICCS 2009 - Baton Rouge, LA, United States Duration: May 25 2009 → May 27 2009

Publication series

Name	Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Number	PART 2
Volume	5545 LNCS
ISSN (Print)	0302-9743
ISSN (Electronic)	1611-3349

Other

Other	9th International Conference on Computational Science, ICCS 2009
Country/Territory	United States
City	Baton Rouge, LA
Period	5/25/09 → 5/27/09

Keywords

Charge transfer
Counterions
DNA hairpin

ASJC Scopus subject areas

Theoretical Computer Science
General Computer Science

Access to Document

10.1007/978-3-642-01973-9_21

Cite this

Blaustein, G. S., Lewis, F. D., Burin, A. L., & Shrestha, R. (2009). The kinetics of charge recombination in DNA hairpins controlled by counterions. In Computational Science - ICCS 2009 - 9th International Conference, Proceedings (PART 2 ed., pp. 189-196). (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 5545 LNCS, No. PART 2). https://doi.org/10.1007/978-3-642-01973-9_21

Blaustein, Gail S. ; Lewis, Frederick D. ; Burin, Alexander L. et al. / The kinetics of charge recombination in DNA hairpins controlled by counterions. Computational Science - ICCS 2009 - 9th International Conference, Proceedings. PART 2. ed. 2009. pp. 189-196 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2).

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title = "The kinetics of charge recombination in DNA hairpins controlled by counterions",

abstract = "The charge recombination rate in DNA hairpins is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd ∈+∈) and stilbene acceptor (Sa-) linkers separated by an AT bridge has a double exponential form. We suggest that this dependence is associated with two tunneling channels distinguished by the presence or absence of the Cl- counterion bound to Sd ∈+∈. Experiment-based estimates of counterion binding parameters agree within reasonable expectations. A control experiment replacing the Cl- ion with other halide ions is suggested. Counterion substitution allows modification of the charge recombination rate in either direction by orders of magnitude.",

keywords = "Charge transfer, Counterions, DNA hairpin",

author = "Blaustein, {Gail S.} and Lewis, {Frederick D.} and Burin, {Alexander L.} and Rajesh Shrestha",

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series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",

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Blaustein, GS, Lewis, FD, Burin, AL & Shrestha, R 2009, The kinetics of charge recombination in DNA hairpins controlled by counterions. in Computational Science - ICCS 2009 - 9th International Conference, Proceedings. PART 2 edn, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), no. PART 2, vol. 5545 LNCS, pp. 189-196, 9th International Conference on Computational Science, ICCS 2009, Baton Rouge, LA, United States, 5/25/09. https://doi.org/10.1007/978-3-642-01973-9_21

The kinetics of charge recombination in DNA hairpins controlled by counterions. / Blaustein, Gail S.; Lewis, Frederick D.; Burin, Alexander L. et al.
Computational Science - ICCS 2009 - 9th International Conference, Proceedings. PART 2. ed. 2009. p. 189-196 (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); Vol. 5545 LNCS, No. PART 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

TY - GEN

T1 - The kinetics of charge recombination in DNA hairpins controlled by counterions

AU - Blaustein, Gail S.

AU - Lewis, Frederick D.

AU - Burin, Alexander L.

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N2 - The charge recombination rate in DNA hairpins is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd ∈+∈) and stilbene acceptor (Sa-) linkers separated by an AT bridge has a double exponential form. We suggest that this dependence is associated with two tunneling channels distinguished by the presence or absence of the Cl- counterion bound to Sd ∈+∈. Experiment-based estimates of counterion binding parameters agree within reasonable expectations. A control experiment replacing the Cl- ion with other halide ions is suggested. Counterion substitution allows modification of the charge recombination rate in either direction by orders of magnitude.

AB - The charge recombination rate in DNA hairpins is investigated. The distance dependence for the charge recombination rate between stilbene donor (Sd ∈+∈) and stilbene acceptor (Sa-) linkers separated by an AT bridge has a double exponential form. We suggest that this dependence is associated with two tunneling channels distinguished by the presence or absence of the Cl- counterion bound to Sd ∈+∈. Experiment-based estimates of counterion binding parameters agree within reasonable expectations. A control experiment replacing the Cl- ion with other halide ions is suggested. Counterion substitution allows modification of the charge recombination rate in either direction by orders of magnitude.

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KW - DNA hairpin

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Blaustein GS, Lewis FD, Burin AL, Shrestha R. The kinetics of charge recombination in DNA hairpins controlled by counterions. In Computational Science - ICCS 2009 - 9th International Conference, Proceedings. PART 2 ed. 2009. p. 189-196. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); PART 2). doi: 10.1007/978-3-642-01973-9_21

The kinetics of charge recombination in DNA hairpins controlled by counterions

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