The Longitudinal Chronic Kidney Disease Study: A Prospective Cohort Study of Predialysis Renal Failure

Rachel L. Perlman, Margaret Kiser, Fredric Finkelstein, George Eisele, Erik Roys, Lei Liu, Sally Burrows-Hudson, Friedrich Port, Joseph M. Messana, George Bailie, Sanjay Rajagopalan, Rajiv Saran*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

Chronic kidney disease (CKD) is a significant public health problem: every year the number of Americans living with CKD and requiring renal replacement therapy increases. In addition, individuals with CKD have substantially increased morbidity and mortality compared to the general population. The Longitudinal Chronic Kidney Dialysis (LCKD) Study is a multicenter, prospective, observational study of patients with moderate to severe CKD that was designed to better describe the course of the disease and the determinants of patient outcomes. Patients with moderate to severe CKD (glomerular filtration rate [GFR] < 60 ml/min/m2) from four academic nephrology clinics were enrolled between 2000 and 2002. Special cardiac and vascular testing has recently commenced as phase II of this study. Areas that have been or are currently being studied include anemia management, health-related quality of life (HRQOL), medication use, and markers of cardiovascular disease. This article describes the LCKD Study in the context of current knowledge of CKD.

Original languageEnglish (US)
Pages (from-to)418-423
Number of pages6
JournalSeminars in Dialysis
Volume16
Issue number6
DOIs
StatePublished - Nov 1 2003

ASJC Scopus subject areas

  • Nephrology

Fingerprint Dive into the research topics of 'The Longitudinal Chronic Kidney Disease Study: A Prospective Cohort Study of Predialysis Renal Failure'. Together they form a unique fingerprint.

Cite this