The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics

A. Wautlet; C. Bachert; M. Desrosiers; Peter W. Hellings; Anju T. Peters

doi:10.1016/j.jaip.2023.04.054

The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics

A. Wautlet, C. Bachert, M. Desrosiers, Peter W. Hellings, Anju T. Peters^*

^*Corresponding author for this work

Medicine, Allergy Division

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide population. This illness is associated with several chronic conditions and has an important impact on patient quality of life, leading to a great societal economic burden. In recent years, biologic medications have been developed and found to be effective in the treatment of chronic rhinosinusitis with nasal polyps. This review focuses on these treatment options and their ability to improve patient outcomes, including quality of life. It also reviews available evidence with regards to patient selection, monitoring of patients after treatment initiation, and comparison of different biologics and with other treatment options such as sinus surgery.

Original language	English (US)
Pages (from-to)	2642-2651
Number of pages	10
Journal	Journal of Allergy and Clinical Immunology: In Practice
Volume	11
Issue number	9
DOIs	https://doi.org/10.1016/j.jaip.2023.04.054
State	Published - Sep 2023

Funding

This work was supported by the Chronic Rhinosinusitis Integrated Studies Program 2 (grant P01AI145818) and the Ernest Bazley Foundation.

Keywords

Biologics
Chronic rhinosinusitis
Nasal polyps

ASJC Scopus subject areas

Immunology and Allergy

Access to Document

10.1016/j.jaip.2023.04.054

Cite this

@article{33a6530b45a14d3babb5a1b9dbc9e946,

title = "The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics",

abstract = "Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide population. This illness is associated with several chronic conditions and has an important impact on patient quality of life, leading to a great societal economic burden. In recent years, biologic medications have been developed and found to be effective in the treatment of chronic rhinosinusitis with nasal polyps. This review focuses on these treatment options and their ability to improve patient outcomes, including quality of life. It also reviews available evidence with regards to patient selection, monitoring of patients after treatment initiation, and comparison of different biologics and with other treatment options such as sinus surgery.",

keywords = "Biologics, Chronic rhinosinusitis, Nasal polyps",

author = "A. Wautlet and C. Bachert and M. Desrosiers and Hellings, {Peter W.} and Peters, {Anju T.}",

note = "Publisher Copyright: {\textcopyright} 2023",

year = "2023",

month = sep,

doi = "10.1016/j.jaip.2023.04.054",

language = "English (US)",

volume = "11",

pages = "2642--2651",

journal = "Journal of Allergy and Clinical Immunology: In Practice",

issn = "2213-2198",

publisher = "American Academy of Allergy, Asthma and Immunology",

number = "9",

}

TY - JOUR

T1 - The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics

AU - Wautlet, A.

AU - Bachert, C.

AU - Desrosiers, M.

AU - Hellings, Peter W.

AU - Peters, Anju T.

PY - 2023/9

Y1 - 2023/9

N2 - Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide population. This illness is associated with several chronic conditions and has an important impact on patient quality of life, leading to a great societal economic burden. In recent years, biologic medications have been developed and found to be effective in the treatment of chronic rhinosinusitis with nasal polyps. This review focuses on these treatment options and their ability to improve patient outcomes, including quality of life. It also reviews available evidence with regards to patient selection, monitoring of patients after treatment initiation, and comparison of different biologics and with other treatment options such as sinus surgery.

AB - Chronic rhinosinusitis with nasal polyps affects a significant portion of the worldwide population. This illness is associated with several chronic conditions and has an important impact on patient quality of life, leading to a great societal economic burden. In recent years, biologic medications have been developed and found to be effective in the treatment of chronic rhinosinusitis with nasal polyps. This review focuses on these treatment options and their ability to improve patient outcomes, including quality of life. It also reviews available evidence with regards to patient selection, monitoring of patients after treatment initiation, and comparison of different biologics and with other treatment options such as sinus surgery.

KW - Biologics

KW - Chronic rhinosinusitis

KW - Nasal polyps

UR - http://www.scopus.com/inward/record.url?scp=85163332786&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85163332786&partnerID=8YFLogxK

U2 - 10.1016/j.jaip.2023.04.054

DO - 10.1016/j.jaip.2023.04.054

M3 - Article

C2 - 37182568

AN - SCOPUS:85163332786

SN - 2213-2198

VL - 11

SP - 2642

EP - 2651

JO - Journal of Allergy and Clinical Immunology: In Practice

JF - Journal of Allergy and Clinical Immunology: In Practice

IS - 9

ER -

The Management of Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) With Biologics

Abstract

Funding

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this