The micromechanics of DNA

John F. Marko*, Simona Cocco

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

42 Scopus citations


The combination of biochemistry with physical concepts and instrumentation leading to new insights into how DNA is organized and processes inside cells are presented. Experiments on single molecules of DNA provided a mechanistic view of DNA-processing enzymes. The single molecule experiment emphasized thermal motion and the disorder that is inherent in large bio-polymers giving each enzyme-DNA interaction a unique timeframe and outcome.

Original languageEnglish
Pages (from-to)37-41
Number of pages5
JournalPhysics World
Issue number3
StatePublished - Mar 2003

ASJC Scopus subject areas

  • Physics and Astronomy(all)

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