The mRNA level of the circadian regulated Gonyaulax luciferase remains constant over the cycle

Maria Mittag; Liming Li; J. Woodland Hastings

doi:10.3109/07420529808998673

The mRNA level of the circadian regulated Gonyaulax luciferase remains constant over the cycle

Maria Mittag, Liming Li, J. Woodland Hastings

Biochemistry and Molecular Genetics

Research output: Contribution to journal › Article › peer-review

44 Scopus citations

Abstract

The expression of luciferin-binding protein (LBP) and luciferase (LCF), two proteins that are involved in bioluminescence in Gonyaulax polyedra, is controlled by a cellular circadian clock. In the case of LBP, its temporal expression is reported to be regulated at the translational level, involving both 5' and 3' untranslated regions (UTRs) of lbp mRNA. Here, we show that the amounts of lcf mRNA are constant throughout the day-night cycle, indicating that the circadian expression of LCF is also regulated at the translational level.

Original language	English (US)
Pages (from-to)	93-98
Number of pages	6
Journal	Chronobiology International
Volume	15
Issue number	1
DOIs	https://doi.org/10.3109/07420529808998673
State	Published - 1998

Funding

This research was supported in part by grants from the National Science Foundation (MCB 96 31935) and the Office of Naval Research (N00014-94-10575). The pDL104 was kindly provided by Dr. D.-H. Lee. M.M. was the recipient of a postdoctoral fellowship (Mi373/1) and a habilitation fellowship (373/2) from the Deutsche Forschung-sgemeinschaft.

ASJC Scopus subject areas

Physiology
Physiology (medical)

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title = "The mRNA level of the circadian regulated Gonyaulax luciferase remains constant over the cycle",

abstract = "The expression of luciferin-binding protein (LBP) and luciferase (LCF), two proteins that are involved in bioluminescence in Gonyaulax polyedra, is controlled by a cellular circadian clock. In the case of LBP, its temporal expression is reported to be regulated at the translational level, involving both 5' and 3' untranslated regions (UTRs) of lbp mRNA. Here, we show that the amounts of lcf mRNA are constant throughout the day-night cycle, indicating that the circadian expression of LCF is also regulated at the translational level.",

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note = "Funding Information: This research was supported in part by grants from the National Science Foundation (MCB 96 31935) and the Office of Naval Research (N00014-94-10575). The pDL104 was kindly provided by Dr. D.-H. Lee. M.M. was the recipient of a postdoctoral fellowship (Mi373/1) and a habilitation fellowship (373/2) from the Deutsche Forschung-sgemeinschaft.",

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AU - Li, Liming

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N2 - The expression of luciferin-binding protein (LBP) and luciferase (LCF), two proteins that are involved in bioluminescence in Gonyaulax polyedra, is controlled by a cellular circadian clock. In the case of LBP, its temporal expression is reported to be regulated at the translational level, involving both 5' and 3' untranslated regions (UTRs) of lbp mRNA. Here, we show that the amounts of lcf mRNA are constant throughout the day-night cycle, indicating that the circadian expression of LCF is also regulated at the translational level.

AB - The expression of luciferin-binding protein (LBP) and luciferase (LCF), two proteins that are involved in bioluminescence in Gonyaulax polyedra, is controlled by a cellular circadian clock. In the case of LBP, its temporal expression is reported to be regulated at the translational level, involving both 5' and 3' untranslated regions (UTRs) of lbp mRNA. Here, we show that the amounts of lcf mRNA are constant throughout the day-night cycle, indicating that the circadian expression of LCF is also regulated at the translational level.

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The mRNA level of the circadian regulated Gonyaulax luciferase remains constant over the cycle

Abstract

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