@article{844bd3ac32ab41179b6a02f678e94429,
title = "The national emphysema treatment trial: A paradigm for future surgical trials",
author = "Wood, {Douglas E.} and DeCamp, {Malcolm M.}",
note = "Funding Information: It is this setting in which the National Emphysema Treatment Trial (NETT) was initiated. The NETT is a prospective, randomized, multiinstitutional clinical trial that compares medical therapy for emphysema to medical therapy plus LVRS. The trial is supported by an historic collaboration between the Health Care Financing Administration (HCFA; Medicare) and the NIH, with the cost of allowable clinical services reimbursed by Medicare, and the NIH supporting the cost of the associated research questions. Seventeen clinical centers are involved in the trial and have a recruitment goal to achieve randomization of 2,500 patients in the 5 years of the study. The primary outcome measures are survival and maximum exercise capacity, and secondary outcome measures examine quality of life, disease-specific symptoms, cost-effectiveness, pulmonary function, gas exchange, oxygen utilization, radiologic assessments, and psychomotor function. ",
year = "2001",
doi = "10.1016/S0003-4975(01)02396-7",
language = "English (US)",
volume = "72",
pages = "327--329",
journal = "Annals of Thoracic Surgery",
issn = "0003-4975",
publisher = "Elsevier USA",
number = "2",
}