The neuronal response to electrical constant-amplitude pulse train stimulation: Additive Gaussian noise

A. J. Matsuoka*, P. J. Abbas, J. T. Rubinstein, C. A. Miller

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Experimental results from humans and animals show that electrically evoked compound action potential (EAP) responses to constant-amplitude pulse train stimulation can demonstrate an alternating pattern, due to the combined effects of highly synchronized responses to electrical stimulation and refractory effects (Wilson et al., 1994). One way to improve signal representation is to reduce the level of across-fiber synchrony and hence, the level of the amplitude alternation. To accomplish this goal, we have examined EAP responses in the presence of Gaussian noise added to the pulse train stimulus. Addition of Gaussian noise at a level approximately -30 dB relative to EAP threshold to the pulse trains decreased the amount of alternation, indicating that stochastic resonance may be induced in the auditory nerve. The use of some type of conditioning stimulus such as Gaussian noise may provide a more 'normal' neural response pattern. Copyright (C) 2000 Elsevier Science B.V.

Original languageEnglish (US)
Pages (from-to)129-137
Number of pages9
JournalHearing research
Volume149
Issue number1-2
DOIs
StatePublished - Oct 13 2000

Keywords

  • Cochlear implant
  • Electrical stimulation
  • Stochastic resonance

ASJC Scopus subject areas

  • Sensory Systems

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