The new antidepressants: Selective serotonin reuptake inhibitors

M. J. Labellarte*, J. T. Walkup, M. A. Riddle

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

26 Scopus citations

Abstract

This article provides a resource for choosing among available SSRIs to treat pediatric patients. SSRIs are addressed according to five areas of interest: treatment efficacy data, untoward effects profile, pharmacokinetic characteristics, potential drug-drug interactions, and cost. Strategies for SSRI dosing and pretreatment work-up are also discussed. Included in the article is a reference table for SSRI dosing, available preparations, and cost per dose. Also included is an abbreviated reference table of important cytochrome P-450 isoenzymes, isoenzyme inhibition by SSRIs, and selected psychotropic and somatic medication substrates.

Original languageEnglish (US)
Pages (from-to)1137-1155
Number of pages19
JournalPediatric Clinics of North America
Volume45
Issue number5
DOIs
StatePublished - 1998

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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