The Newer Fluoroquinolones

Maureen K Bolon

doi:10.1016/j.mcna.2011.03.006

The Newer Fluoroquinolones

Maureen K Bolon^*

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.

Original language	English (US)
Pages (from-to)	793-817
Number of pages	25
Journal	Medical Clinics of North America
Volume	95
Issue number	4
DOIs	https://doi.org/10.1016/j.mcna.2011.03.006
State	Published - Jul 1 2011

Keywords

Antiinfective agents
Fluoroquinolones
Microbial drug resistance
Pharmacokinetics
Pharmacology
Therapeutic use

ASJC Scopus subject areas

Medicine(all)

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10.1016/j.mcna.2011.03.006

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abstract = "Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.",

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AB - Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.

KW - Antiinfective agents

KW - Fluoroquinolones

KW - Microbial drug resistance

KW - Pharmacokinetics

KW - Pharmacology

KW - Therapeutic use

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The Newer Fluoroquinolones

Abstract

Keywords

ASJC Scopus subject areas

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