The Newer Fluoroquinolones

Maureen K Bolon

doi:10.1016/j.idc.2009.06.003

The Newer Fluoroquinolones

Maureen K Bolon^*

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Review article › peer-review

71 Scopus citations

Abstract

Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.

Original language	English (US)
Pages (from-to)	1027-1051
Number of pages	25
Journal	Infectious Disease Clinics of North America
Volume	23
Issue number	4
DOIs	https://doi.org/10.1016/j.idc.2009.06.003
State	Published - Dec 1 2009

Keywords

Antiinfective agents
Fluoroquinolones
Microbial drug resistance
Pharmacokinetics
Pharmacology
Therapeutic use

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.idc.2009.06.003

Cite this

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title = "The Newer Fluoroquinolones",

abstract = "Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.",

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AB - Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and Streptococcus pneumonia. Important fluoroquinolone safety concerns are discussed, along with indications for the most commonly used fluoroquinolones-ciprofloxacin, levofloxacin, and moxifloxacin.

KW - Antiinfective agents

KW - Fluoroquinolones

KW - Microbial drug resistance

KW - Pharmacokinetics

KW - Pharmacology

KW - Therapeutic use

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AN - SCOPUS:70350726100

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JO - Infectious Disease Clinics of North America

JF - Infectious Disease Clinics of North America

IS - 4

ER -

The Newer Fluoroquinolones

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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