The nuclear pore complex as a platform for epigenetic regulation

Jason H. Brickner*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The nuclear pore complex (NPC) both mediates exchange of proteins and RNA between the nucleus and the cytoplasm and physically interacts with chromatin to regulate transcription. In this issue of JCB, Kumar et al. (2023. J. Cell Biol.https://doi.org/10.1083/jcb.202207060) provide new insight into the molecular basis for NPC-mediated epigenetic silencing through loading of the replication processivity factor PCNA.

Original languageEnglish (US)
Article numbere202307078
JournalJournal of Cell Biology
Volume222
Issue number9
DOIs
StatePublished - Sep 4 2023

ASJC Scopus subject areas

  • Cell Biology

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