The oocyte

Allison R. Grover; Barbara Fegley; Timothy V. Duncan; Francesca E. Duncan

doi:10.1016/B978-0-12-801238-3.64390-8

The oocyte

Allison R. Grover, Barbara Fegley, Timothy V. Duncan, Francesca E. Duncan

Obstetrics and Gynecology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The mammalian oocyte has tremendous potential energy because it is capable of giving rise to an entirely new generation upon fertilization. In addition to providing the embryo with half its DNA content, the oocyte also endows the early embryo with the majority of its cellular volume because the sperm volume is orders of magnitude smaller. The cellular volume of the oocyte contains critical maternal products that are essential for supporting the developmental events of meiosis, fertilization, and early embryo development. In this article, we review the cellular architecture of the mammalian oocyte, key biological processes that dictate the developmental potential of the oocyte, and physiological and extrinsic factors that can impact oocyte quality.

Original language	English (US)
Title of host publication	Encyclopedia of Reproduction
Publisher	Elsevier
Pages	21-28
Number of pages	8
ISBN (Electronic)	9780128151457
DOIs	https://doi.org/10.1016/B978-0-12-801238-3.64390-8
State	Published - Jan 1 2018

Keywords

Aging
Bisphenol a
Cortical granules
Cytoplasmic lattice
Egg
Fertilization
Germinal vesicle
Meiosis
Obesity
Oncofertility
Oocyte
Organelles
Polycystic ovarian syndrome
Transzonal projection
Zona pellucida

ASJC Scopus subject areas

Medicine(all)

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10.1016/B978-0-12-801238-3.64390-8

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Grover, A. R., Fegley, B., Duncan, T. V., & Duncan, F. E. (2018). The oocyte. In Encyclopedia of Reproduction (pp. 21-28). Elsevier. https://doi.org/10.1016/B978-0-12-801238-3.64390-8

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