The pathology of the chronic lymphoid leukaemias

S. H. Kroft*, W. G. Finn, Lo Ann C. Peterson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

The chronic lymphoid leukaemias, though they all possess relatively mature lymphoid phenotypes, are a diverse group of diseases at the clinical, morphological, immunophenotypical, and biological levels. Generally accepted entities within this category include B-cell. chronic lymphocytic leukaemia of classical and mixed-cell types, B-cell and T-cell prolymphocytic leukaemia, hairy-cell leukaemia and hairy-cell variant, splenic lymphoma with circulating villous lymphocytes, large granular lymphocytic leukaemia, adult T-cell leukaemia/lymphoma syndrome, and leukaemic phases of malignant lymphomas of both B-cell and T-cell types. Recent advances have helped to differentiate these diseases, allowing the development of more specific therapy and more accurate prognostication. In this article, we review the pathological aspects of these diseases.

Original languageEnglish (US)
Pages (from-to)234-250
Number of pages17
JournalBlood Reviews
Volume9
Issue number4
DOIs
StatePublished - Dec 1995

ASJC Scopus subject areas

  • Hematology
  • Oncology

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