The regulation of electrolytes and water in the newborn are presented in this article, concentrating on those features that differ in the immature and mature human and those aspects that are important to understanding diuretic effects. The pathophysiology of water and sodium balance in various disorders serves to present the indications for diuretic therapy. The pharmacodynamics of individual diuretic agents is presented, and the pharmacokinetics and toxicity of the commonly used agents is discussed.
|Original language||English (US)|
|Number of pages||14|
|Journal||Clinics in Perinatology|
|State||Published - Dec 1 1987|
ASJC Scopus subject areas
- Pediatrics, Perinatology, and Child Health
- Obstetrics and Gynecology