The potential role of a self-management intervention for ulcerative colitis: A brief report from the ulcerative colitis hypnotherapy trial

Laurie Keefer*, Jennifer L. Kiebles, Monika A. Kwiatek, Olafur Palsson, Tiffany Noel Taft, Zoran Martinovich, Terrence A. Barrett

*Corresponding author for this work

Research output: Contribution to journalArticle

26 Citations (Scopus)

Abstract

Inflammatory bowel diseases (IBD) are chronic inflammatory illnesses marked by unpredictable disease flares, which occur spontaneously and/or in response to external triggers, especially personal health behaviors. Behavioral triggers of flare may be responsive to disease self-management programs. We report on interim findings of a randomized controlled trial of gut-directed hypnotherapy (HYP, n = 19) versus active attention control (CON, n = 17) for quiescent ulcerative colitis (UC). To date, 43 participants have enrolled; after 5 discontinuations (1 in HYP) and 2 exclusions due to excessive missing data, 36 were included in this preliminary analysis. Aim 1 was to determine the feasibility and acceptability of HYP in UC. This was achieved, demonstrated by a reasonable recruitment rate at our outpatient tertiary care clinic (20%), high retention rate (88% total), and our representative IBD sample, which is reflected by an equal distribution of gender, an age range between 21 and 69, recruitment of ethnic minorities ({reversed tilde}20%), and disease duration ranging from 1.5 to 35 years. Aim 2 was to estimate effect sizes on key clinical outcomes for use in future trials. Effect sizes (group × time at 20 weeks) were small to medium for IBD self-efficacy (.34), Inflammatory Bowel Disease Questionnaire (IBDQ) total score (.41), IBDQ bowel (.50), and systemic health (.48). Between-group effects were observed for the IBDQ bowel health subscale (HYP & CON; p =.05) at 20 weeks and the Short Form 12 Health Survey Version 2 (SF-12v2) physical component (HYP & CON; p <.05) at posttreatment and 20 weeks. This study supports future clinical trials testing gut-directed HYP as a relapse prevention tool for IBD.

Original languageEnglish (US)
Pages (from-to)71-77
Number of pages7
JournalBiological research for nursing
Volume14
Issue number1
DOIs
StatePublished - Jan 1 2012

Fingerprint

Hypnosis
Self Care
Ulcerative Colitis
Inflammatory Bowel Diseases
Age Distribution
Health Behavior
Health
Self Efficacy
Tertiary Healthcare
Ambulatory Care
Disease Management
Secondary Prevention
Health Surveys
Chronic Disease
Randomized Controlled Trials
Clinical Trials
Surveys and Questionnaires

Keywords

  • hypnotherapy
  • inflammatory bowel disease
  • self-efficacy
  • self-management
  • ulcerative colitis

ASJC Scopus subject areas

  • Research and Theory

Cite this

Keefer, Laurie ; Kiebles, Jennifer L. ; Kwiatek, Monika A. ; Palsson, Olafur ; Taft, Tiffany Noel ; Martinovich, Zoran ; Barrett, Terrence A. / The potential role of a self-management intervention for ulcerative colitis : A brief report from the ulcerative colitis hypnotherapy trial. In: Biological research for nursing. 2012 ; Vol. 14, No. 1. pp. 71-77.
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The potential role of a self-management intervention for ulcerative colitis : A brief report from the ulcerative colitis hypnotherapy trial. / Keefer, Laurie; Kiebles, Jennifer L.; Kwiatek, Monika A.; Palsson, Olafur; Taft, Tiffany Noel; Martinovich, Zoran; Barrett, Terrence A.

In: Biological research for nursing, Vol. 14, No. 1, 01.01.2012, p. 71-77.

Research output: Contribution to journalArticle

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