The potential use of mechanism-based enzyme inactivators in medicine

Richard B. Silverman

doi:10.3109/14756368809040714

The potential use of mechanism-based enzyme inactivators in medicine

Richard B. Silverman^*

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Original language	English (US)
Pages (from-to)	73-90
Number of pages	18
Journal	Journal of Enzyme Inhibition and Medicinal Chemistry
Volume	2
Issue number	2
DOIs	https://doi.org/10.3109/14756368809040714
State	Published - 1988

Keywords

Alanine racemase
Arginine decarboxylase
Aromatase
D-amino acid aminotransferase
Dihydrofolate reductase
Dihydroorotate dehydrogenase DNA polymerase I
Dopamine βhydroxylase
Histidine decarboxylase
L-aromatic amino acid decarboxylase
Mechanism-based enzyme inactivator
Monoamine oxidase
Ornithine decarboxylase
S-adenosylhomocysteine hydrolase
Serine proteases
Testosterone 5αreductase
Thymidylate synthetase
Xanthine oxidase
βlactamase
γaminobutyric acid aminotransferase

ASJC Scopus subject areas

Pharmacology
Drug Discovery

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title = "The potential use of mechanism-based enzyme inactivators in medicine",

keywords = "Alanine racemase, Arginine decarboxylase, Aromatase, D-amino acid aminotransferase, Dihydrofolate reductase, Dihydroorotate dehydrogenase DNA polymerase I, Dopamine βhydroxylase, Histidine decarboxylase, L-aromatic amino acid decarboxylase, Mechanism-based enzyme inactivator, Monoamine oxidase, Ornithine decarboxylase, S-adenosylhomocysteine hydrolase, Serine proteases, Testosterone 5αreductase, Thymidylate synthetase, Xanthine oxidase, βlactamase, γaminobutyric acid aminotransferase",

author = "Silverman, {Richard B.}",

year = "1988",

doi = "10.3109/14756368809040714",

language = "English (US)",

volume = "2",

pages = "73--90",

journal = "Journal of Enzyme Inhibition and Medicinal Chemistry",

issn = "1475-6366",

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TY - JOUR

T1 - The potential use of mechanism-based enzyme inactivators in medicine

AU - Silverman, Richard B.

PY - 1988

Y1 - 1988

KW - Alanine racemase

KW - Arginine decarboxylase

KW - Aromatase

KW - D-amino acid aminotransferase

KW - Dihydrofolate reductase

KW - Dihydroorotate dehydrogenase DNA polymerase I

KW - Dopamine βhydroxylase

KW - Histidine decarboxylase

KW - L-aromatic amino acid decarboxylase

KW - Mechanism-based enzyme inactivator

KW - Monoamine oxidase

KW - Ornithine decarboxylase

KW - S-adenosylhomocysteine hydrolase

KW - Serine proteases

KW - Testosterone 5αreductase

KW - Thymidylate synthetase

KW - Xanthine oxidase

KW - βlactamase

KW - γaminobutyric acid aminotransferase

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U2 - 10.3109/14756368809040714

DO - 10.3109/14756368809040714

M3 - Article

C2 - 3069967

AN - SCOPUS:84907115993

SN - 1475-6366

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SP - 73

EP - 90

JO - Journal of Enzyme Inhibition and Medicinal Chemistry

JF - Journal of Enzyme Inhibition and Medicinal Chemistry

IS - 2

ER -

The potential use of mechanism-based enzyme inactivators in medicine

Keywords

ASJC Scopus subject areas

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