The problem of resistance in Mycobacterium tuberculosis may be underestimated in Africa

Simeon I.B. Cadmus*, Olutayo I. Falodun, Oba E. Fagade, Robert Murphy, Babafemi Taiwo, Dick Van Soolingen

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background: The true burden of tuberculosis (TB) and particularly multidrug-resistant (MDR) TB in Sub-Saharan Africa has remained underestimated. Methods: We investigated drug susceptibility profile and genetic diversity of Mycobacterium tuberculosis isolates collected from confirmed tuberculosis patients in Ibadan, southwestern Nigeria. Results: We confirmed that from 74 randomly selected Mycobacterium tuberculosis isolates available for drug susceptibility testing in Ibadan, in 2011, 13.5% of them were MDR-TB. Conclusions: This figure is obviously above the national and World Health Organization figures.

Original languageEnglish (US)
Pages (from-to)148-151
Number of pages4
JournalInternational Journal of Mycobacteriology
Volume7
Issue number2
DOIs
StatePublished - Apr 1 2018

Keywords

  • Africa
  • Nigeria
  • drug resistance
  • tuberculosis

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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