The relationship between obstructive sleep apnea, nocturia, and daytime overactive bladder syndrome in women

Lior Lowenstein*, Kimberly Kenton, Linda Brubaker, Giora Pillar, Nidhi Undevia, Elizabeth R. Mueller, Mary Pat FitzGerald

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

36 Scopus citations

Abstract

Objective: The purpose of this study was to corroborate the association between obstructive sleep apnea (OSA) and nocturia in a clinical sample of urogynecologic patients and to explore whether night-time urine concentration predicts the presence of OSA. Study Design: Patients with nocturia and control subjects underwent a home sleep study, completed validated nocturia questionnaires, and provided evening and morning urine specimens that were analyzed for osmolarity. Results: Twenty-one patients with nocturia (16 of whom also had daytime overactive bladder [OAB] symptoms) and 10 control subjects were studied. OSA was present in 17 of 21 women (81%) with nocturia: 13 women (81%) with OAB, 4 women (80%) with nocturia/no OAB, and 4 control subjects (40%; P < .001). The percentage of rapid eye movement sleep time was correlated inversely with nocturic frequency (ρ = -.51; P < .004). The presence of diluted nighttime urine in a patient with nocturia was 88% sensitive for the presence of OSA. Conclusion: We should consider a diagnosis of OSA in all patients with nocturia, even those patients with daytime OAB.

Original languageEnglish (US)
Pages (from-to)598.e1-598.e5
JournalAmerican journal of obstetrics and gynecology
Volume198
Issue number5
DOIs
StatePublished - May 2008

Keywords

  • nocturia
  • obstructive sleep apnea
  • overactive bladder syndrome
  • sleep study

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Fingerprint Dive into the research topics of 'The relationship between obstructive sleep apnea, nocturia, and daytime overactive bladder syndrome in women'. Together they form a unique fingerprint.

Cite this