Abstract
A novel mathematical model for hepatocytes and surrounding volume is presented here; in addition to tracking ion transport and diffusion the new model allows for changing cell volume. Using temporally and spatially varying temperature as an input, this paper shows how differences between diffusion coefficients directly influence increases in cell volume. The multiscale nature of the model presents a possible link from established cellular equations to the observed clinical result of oedema present in thermal treatments of cancer.
Original language | English (US) |
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Title of host publication | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 |
Pages | 4305-4308 |
Number of pages | 4 |
DOIs | |
State | Published - Dec 26 2011 |
Event | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 - Boston, MA, United States Duration: Aug 30 2011 → Sep 3 2011 |
Other
Other | 33rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2011 |
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Country/Territory | United States |
City | Boston, MA |
Period | 8/30/11 → 9/3/11 |
ASJC Scopus subject areas
- Signal Processing
- Biomedical Engineering
- Computer Vision and Pattern Recognition
- Health Informatics