The RING finger domain: A recent example of a sequence-structure family

Katherine L.B. Borden*, Paul S. Freemont

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

428 Scopus citations

Abstract

In the past 18 months, two RING finger structures have been solved. They represent the first reported structures for this novel zinc-binding sequence motif. Both structures are significantly different from other zinc-binding domains, in terms of both their zinc-ligation scheme and their three-dimensional structures. The RING finger domain appears to be a convenient scaffold which can be altered to provide functional specificity in those proteins that contain the motif.

Original languageEnglish (US)
Pages (from-to)395-401
Number of pages7
JournalCurrent Opinion in Structural Biology
Volume6
Issue number3
DOIs
StatePublished - Jun 1996

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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