The role of adhesion molecules in allergic inflammation and their suitability as targets of antiallergic therapy

R. P. Schleimer*, B. S. Bochner

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

48 Scopus citations

Abstract

Adhesion molecules on leukocytes and tissue-resident cells are now known to mediate steps of the allergic inflammation response. Blockade of adhesion pathways is being actively explored as a potential strategy to therapeutically manage allergic diseases. The various adhesion molecules and their counterligands are discussed with respect to evidence supporting their role in allergic inflammation and suitability as therapeutic targets.

Original languageEnglish (US)
Pages (from-to)15-23
Number of pages9
JournalClinical and Experimental Allergy, Supplement
Volume28
Issue number3
StatePublished - Aug 1 1998

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology

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