The role of clinical trials in the development of novel surgical techniques

Heidi Nelson*, Anne Marie Boller

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

4 Scopus citations

Abstract

The new paradigm and standard for medicine and surgery is the evidence-based practice for which the randomized controlled trial is fundamental. Despite the early involvement of surgeons in clinical trials, randomized trials testing novel surgical therapies are not common. Indeed, only 24% of surgical patients are managed based on level 1 evidence. This chapter details how randomized controlled trial methodologies facilitate the development of level 1 evidence in support of minimally invasive colon cancer surgery.

Original languageEnglish (US)
Pages (from-to)704-709
Number of pages6
JournalJournal of surgical oncology
Volume96
Issue number8
DOIs
StatePublished - Dec 15 2007

Keywords

  • Evidence-based surgery
  • Prospective trials
  • Randomized controlled trials

ASJC Scopus subject areas

  • Oncology
  • Surgery

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