The role of mesalazine in crohn's disease

Sb Hanauer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Sulfasalazine continues to be a common treatment for active Crohn's disease. It has been shown to be more effective than placebo in patients with colonic disease and in patients without prior surgical resection. There is no clear clinical evidence for its use as maintenance therapy in quiescent Crohn's disease; nevertheless, it is widely used to prevent symptom recurrence in patients whose active disease responded to sulfasalazine. In a few preliminary controlled studies, mesalazine has been shown to be superior to placebo in the treatment of active Crohn's disease. Until recently, the results of trials of mesalazine as maintenance therapy in quiescent Crohn's disease were equivocal but promising.

Original languageEnglish (US)
Pages (from-to)56-59
Number of pages4
JournalScandinavian Journal of Gastroenterology
Volume25
Issue numberS172
DOIs
StatePublished - Jan 1 1990

Keywords

  • Crohn's disease
  • Mesalazine
  • Sulfasalazine

ASJC Scopus subject areas

  • Gastroenterology

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