A chiral 30-crown-10 derivative, DD-(2), has been prepared from 1,4:3,6-dianhydro-D-mannitol, D-(1), and shown by X-ray crystallography and dynamic 13C n.m.r. spectroscopy to adopt, in both the solid state and in solution, a 'face-to-back' conformation which must undergo substantial change in order to create the hydrophilic cavity necessary for the formation of complexes with Li+, Na+, K+, Rb+, NH4+, MeNH3+, and Bu tNH3+ ions.
|Original language||English (US)|
|Number of pages||3|
|Journal||Journal of the Chemical Society, Chemical Communications|
|State||Published - 1981|
ASJC Scopus subject areas
- Molecular Medicine