TY - JOUR
T1 - The state of the STATs
T2 - Recent developments in the study of signal transduction to the nucleus
AU - Horvath, Curt M.
AU - Darnell, James E.
PY - 1997/4
Y1 - 1997/4
N2 - The STATs (signal transducers and activators of transcription) are latent cytoplasmic proteins that, upon activation by cell surface bound polypeptide ligands, move to the nucleus to direct transcription. A variety of protein-protein interactions that affect the function of STATs has been recently recognized. It has become clear that the STATs are functional mosaics, or mixtures of signal transduction and transcription modules.
AB - The STATs (signal transducers and activators of transcription) are latent cytoplasmic proteins that, upon activation by cell surface bound polypeptide ligands, move to the nucleus to direct transcription. A variety of protein-protein interactions that affect the function of STATs has been recently recognized. It has become clear that the STATs are functional mosaics, or mixtures of signal transduction and transcription modules.
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U2 - 10.1016/S0955-0674(97)80067-1
DO - 10.1016/S0955-0674(97)80067-1
M3 - Article
C2 - 9069254
AN - SCOPUS:0030962017
SN - 0955-0674
VL - 9
SP - 233
EP - 239
JO - Current Opinion in Cell Biology
JF - Current Opinion in Cell Biology
IS - 2
ER -