The successful use of low-dose recombinant tissue plasminogen activator for treatment of intracardiac/pulmonary thrombosis during liver transplantation

James D. Boone; Saadia S. Sherwani; Joshua C. Herborn; Kinjal M. Patel; Andre M. De Wolf

doi:10.1213/ANE.0b013e31820472d4

The successful use of low-dose recombinant tissue plasminogen activator for treatment of intracardiac/pulmonary thrombosis during liver transplantation

James D. Boone, Saadia S. Sherwani, Joshua C. Herborn, Kinjal M. Patel, Andre M. De Wolf

Anesthesiology

Research output: Contribution to journal › Article › peer-review

41 Scopus citations

Abstract

Intracardiac thrombosis and pulmonary embolism are uncommon complications during liver transplantation but carry a high mortality rate. We report the successful use of low-dose recombinant tissue plasminogen activator (0.5-4 mg) administration in 4 patients. Early diagnosis through transesophageal echocardiography and pulmonary artery catheterization may have contributed to the rapid thrombolysis.

Original language	English (US)
Pages (from-to)	319-321
Number of pages	3
Journal	Anesthesia and analgesia
Volume	112
Issue number	2
DOIs	https://doi.org/10.1213/ANE.0b013e31820472d4
State	Published - Feb 2011

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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abstract = "Intracardiac thrombosis and pulmonary embolism are uncommon complications during liver transplantation but carry a high mortality rate. We report the successful use of low-dose recombinant tissue plasminogen activator (0.5-4 mg) administration in 4 patients. Early diagnosis through transesophageal echocardiography and pulmonary artery catheterization may have contributed to the rapid thrombolysis.",

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AU - De Wolf, Andre M.

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AB - Intracardiac thrombosis and pulmonary embolism are uncommon complications during liver transplantation but carry a high mortality rate. We report the successful use of low-dose recombinant tissue plasminogen activator (0.5-4 mg) administration in 4 patients. Early diagnosis through transesophageal echocardiography and pulmonary artery catheterization may have contributed to the rapid thrombolysis.

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The successful use of low-dose recombinant tissue plasminogen activator for treatment of intracardiac/pulmonary thrombosis during liver transplantation

Abstract

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