The successful use of low-dose recombinant tissue plasminogen activator for treatment of intracardiac/pulmonary thrombosis during liver transplantation

James D. Boone, Saadia S. Sherwani, Joshua C. Herborn, Kinjal M. Patel, Andre M. De Wolf

Research output: Contribution to journalArticlepeer-review

35 Scopus citations

Abstract

Intracardiac thrombosis and pulmonary embolism are uncommon complications during liver transplantation but carry a high mortality rate. We report the successful use of low-dose recombinant tissue plasminogen activator (0.5-4 mg) administration in 4 patients. Early diagnosis through transesophageal echocardiography and pulmonary artery catheterization may have contributed to the rapid thrombolysis.

Original languageEnglish (US)
Pages (from-to)319-321
Number of pages3
JournalAnesthesia and analgesia
Volume112
Issue number2
DOIs
StatePublished - Feb 2011

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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