TY - JOUR
T1 - The synthesis and receptor binding affinities of DDD-016, a novel, potential, atypical antipsychotic
AU - Bandyopadhyaya, Achintya
AU - Rajagopalan, Desikan R.
AU - Rath, Nigam P.
AU - Herrold, Amy
AU - Rajagopalan, Raghavan
AU - Napier, T. Celesete
AU - Tedford, Clark E.
AU - Rajagopalan, Parthasarathi
PY - 2012/5/1
Y1 - 2012/5/1
N2 - A new pentacyclic compound, DDD-016 (10d) was designed and synthesized as a potential antipsychotic and screened for binding affinity in a broad panel of over 80 CNS and other receptors, monoamine transporters, and ion channels. The resulting receptor binding profile of DDD-016 is consistent with that of an improved atypical antipsychotic candidate.
AB - A new pentacyclic compound, DDD-016 (10d) was designed and synthesized as a potential antipsychotic and screened for binding affinity in a broad panel of over 80 CNS and other receptors, monoamine transporters, and ion channels. The resulting receptor binding profile of DDD-016 is consistent with that of an improved atypical antipsychotic candidate.
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UR - http://www.scopus.com/inward/citedby.url?scp=84860446916&partnerID=8YFLogxK
U2 - 10.1039/c2md00311b
DO - 10.1039/c2md00311b
M3 - Article
AN - SCOPUS:84860446916
SN - 2040-2503
VL - 3
SP - 580
EP - 583
JO - MedChemComm
JF - MedChemComm
IS - 5
ER -