The tectorial membrane: Mechanical properties and functions

Jonathan B. Sellon, Roozbeh Ghaffari, Dennis M. Freeman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

The tectorial membrane (TM) is widely believed to play a critical role in determining the remarkable sensitivity and frequency selectivity that are hallmarks of mammalian hearing. Recently developed mouse models of human hearing disorders have provided new insights into the molecular, nanomechanical mechanisms that underlie resonance and traveling wave properties of the TM. Herein we review recent experimental and theoretical results detailing TM morphology, local poroelastic and electromechanical interactions, and global spread of excitation via TM traveling waves, with direct implications for cochlear mechanisms.

Original languageEnglish (US)
Article numbera033514
JournalCold Spring Harbor Perspectives in Medicine
Volume9
Issue number10
DOIs
StatePublished - Oct 2019

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'The tectorial membrane: Mechanical properties and functions'. Together they form a unique fingerprint.

Cite this