TY - JOUR
T1 - The three classes of triplet profiles of natural genomes
AU - Albrecht-Buehler, Guenter
PY - 2007/5
Y1 - 2007/5
N2 - Based on the huge variety of different genomes, one may expect a correspondingly large variety of the frequency distribution of their trinucleotides ("triplet profiles"). Yet, this article reports the unexpected finding that there are essentially only three kinds of triplet profiles among the large number of genomes examined here. None of the classes included random profiles, all of them contained members from vastly different taxa and species. Since the three classes of genomes do not reflect the phylogeny of their member organisms, I propose that these classes may reflect species-independent mechanisms of genome evolution.
AB - Based on the huge variety of different genomes, one may expect a correspondingly large variety of the frequency distribution of their trinucleotides ("triplet profiles"). Yet, this article reports the unexpected finding that there are essentially only three kinds of triplet profiles among the large number of genomes examined here. None of the classes included random profiles, all of them contained members from vastly different taxa and species. Since the three classes of genomes do not reflect the phylogeny of their member organisms, I propose that these classes may reflect species-independent mechanisms of genome evolution.
KW - Genome origin
KW - Phylogeny
KW - Trinucleotide distribution
UR - http://www.scopus.com/inward/record.url?scp=34247130856&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=34247130856&partnerID=8YFLogxK
U2 - 10.1016/j.ygeno.2006.12.009
DO - 10.1016/j.ygeno.2006.12.009
M3 - Article
C2 - 17234378
AN - SCOPUS:34247130856
SN - 0888-7543
VL - 89
SP - 596
EP - 601
JO - Genomics
JF - Genomics
IS - 5
ER -