The turkey ascarid, Ascaridia dissimilis, as a model genetic system

J. B. Collins, Erik C. Andersen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Parasitic nematodes cause significant effects on humans each year, with the most prevalent being Ascaris lumbricoides. Benzimidazoles (BZ) are the most widely used anthelmintic drug in humans, and although the biology of resistance to this drug class is understood in some species, resistance is poorly characterized in ascarids. Models such as Caenorhabditis elegans were essential in developing our current understanding of BZ resistance, but more closely related model nematodes are needed to understand resistance in ascarids. Here, we propose a new ascarid model species that infects turkeys, Ascaridia dissimilis, to develop a better understanding of BZ resistance.

Original languageEnglish (US)
Pages (from-to)405-409
Number of pages5
JournalInternational Journal for Parasitology
Volume53
Issue number8
DOIs
StatePublished - Jul 2023

Keywords

  • Anthelmintic resistance
  • Ascarid
  • Benzimidazole
  • Model organism

ASJC Scopus subject areas

  • Infectious Diseases
  • Parasitology

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