The turkey ascarid, Ascaridia dissimilis, as a model genetic system

J. B. Collins, Erik C. Andersen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Parasitic nematodes cause significant effects on humans each year, with the most prevalent being Ascaris lumbricoides. Benzimidazoles (BZ) are the most widely used anthelmintic drug in humans, and although the biology of resistance to this drug class is understood in some species, resistance is poorly characterized in ascarids. Models such as Caenorhabditis elegans were essential in developing our current understanding of BZ resistance, but more closely related model nematodes are needed to understand resistance in ascarids. Here, we propose a new ascarid model species that infects turkeys, Ascaridia dissimilis, to develop a better understanding of BZ resistance.

Original languageEnglish (US)
JournalInternational Journal for Parasitology
DOIs
StateAccepted/In press - 2022

Keywords

  • Anthelmintic resistance
  • Ascarid
  • Benzimidazole
  • Model organism

ASJC Scopus subject areas

  • Parasitology
  • Infectious Diseases

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