The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms

Rena Yadlapati; Jenna Craft; Christopher J. Adkins; John E. Pandolfino

doi:10.1016/j.cgh.2018.01.031

The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms

Rena Yadlapati^*, Jenna Craft, Christopher J. Adkins, John E. Pandolfino

^*Corresponding author for this work

Medicine, Gastroenterology Division

Research output: Contribution to journal › Short survey › peer-review

11 Scopus citations

Abstract

Reflux-associated laryngeal symptoms (RALS) is the process in which chronic laryngeal symptoms are related to gastroesophagopharyngeal reflux.¹ Impairment of upper esophageal sphincter (UES) reflexes may predispose to esophagopharyngeal reflux.¹ The novel noninvasive nonpharmacologic UES assist device (UESAD) applies external cricoid pressure to augment intraluminal UES pressure by 20 to 30 mm Hg and reduce esophagopharyngeal reflux events.² This study aimed to assess the therapeutic efficacy of the UESAD in a pragmatic clinical setting, and to identify factors associated with symptom response among patients with suspected RALS.

Original language	English (US)
Pages (from-to)	1670-1672
Number of pages	3
Journal	Clinical Gastroenterology and Hepatology
Volume	16
Issue number	10
DOIs	https://doi.org/10.1016/j.cgh.2018.01.031
State	Published - Oct 2018

ASJC Scopus subject areas

Hepatology
Gastroenterology

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10.1016/j.cgh.2018.01.031

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title = "The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms",

abstract = "Reflux-associated laryngeal symptoms (RALS) is the process in which chronic laryngeal symptoms are related to gastroesophagopharyngeal reflux.1 Impairment of upper esophageal sphincter (UES) reflexes may predispose to esophagopharyngeal reflux.1 The novel noninvasive nonpharmacologic UES assist device (UESAD) applies external cricoid pressure to augment intraluminal UES pressure by 20 to 30 mm Hg and reduce esophagopharyngeal reflux events.2 This study aimed to assess the therapeutic efficacy of the UESAD in a pragmatic clinical setting, and to identify factors associated with symptom response among patients with suspected RALS.",

author = "Rena Yadlapati and Jenna Craft and Adkins, {Christopher J.} and Pandolfino, {John E.}",

note = "Funding Information: Funding Supported by National Institutes of Health R01DK092217-04A1 (J.E.P. and R.Y.). Publisher Copyright: {\textcopyright} 2018 AGA Institute",

year = "2018",

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doi = "10.1016/j.cgh.2018.01.031",

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T1 - The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms

AU - Yadlapati, Rena

AU - Craft, Jenna

AU - Adkins, Christopher J.

AU - Pandolfino, John E.

PY - 2018/10

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N2 - Reflux-associated laryngeal symptoms (RALS) is the process in which chronic laryngeal symptoms are related to gastroesophagopharyngeal reflux.1 Impairment of upper esophageal sphincter (UES) reflexes may predispose to esophagopharyngeal reflux.1 The novel noninvasive nonpharmacologic UES assist device (UESAD) applies external cricoid pressure to augment intraluminal UES pressure by 20 to 30 mm Hg and reduce esophagopharyngeal reflux events.2 This study aimed to assess the therapeutic efficacy of the UESAD in a pragmatic clinical setting, and to identify factors associated with symptom response among patients with suspected RALS.

AB - Reflux-associated laryngeal symptoms (RALS) is the process in which chronic laryngeal symptoms are related to gastroesophagopharyngeal reflux.1 Impairment of upper esophageal sphincter (UES) reflexes may predispose to esophagopharyngeal reflux.1 The novel noninvasive nonpharmacologic UES assist device (UESAD) applies external cricoid pressure to augment intraluminal UES pressure by 20 to 30 mm Hg and reduce esophagopharyngeal reflux events.2 This study aimed to assess the therapeutic efficacy of the UESAD in a pragmatic clinical setting, and to identify factors associated with symptom response among patients with suspected RALS.

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DO - 10.1016/j.cgh.2018.01.031

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AN - SCOPUS:85046752338

SN - 1542-3565

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JO - Clinical Gastroenterology and Hepatology

JF - Clinical Gastroenterology and Hepatology

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ER -

The Upper Esophageal Sphincter Assist Device Is Associated With Symptom Response in Reflux-Associated Laryngeal Symptoms

Abstract

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